NSAIDs: Athletes and Exercise
NSAID use should be avoided, especially around training bouts, both due to the potential to mask further damage and because it may negate some of the benefits of training.
NSAID usage also appears to negatively impact bone mineral density when taken in proximity to resistance training. “Ibuprofen consumed immediately after resistance training had a deleterious effect on bone mineral content at the distal radius, whereas resistance training or ibuprofen supplementation individually prevented bone loss. Resistance training prevented muscle density decline in the lower leg.”